cenobamate will enhance the degree or influence of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Check Carefully. Look at a dose reduction of CYP2C19 substrates, as clinically correct, when applied concomitantly with cenobamate.

fentanyl iontophoretic transdermal program and diazepam both equally enhance sedation. Steer clear of or Use Alternate Drug. Limit use to people for whom option remedy options are inadequate

dasatinib will raise the degree or result of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.

Don't acquire APTIOM Should you be allergic to eslicarbazepine acetate, any of the opposite substances in APTIOM, or oxcarbazepine.

Benzodiazepines are simplest when applied early after a seizure starts, on account of alterations at synapses that degrade GABA signaling about time12,thirteen

rifapentine will lessen the extent or effect of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.

topiramate will decrease the level or effect of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

methylprednisolone will lessen the level or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.

voriconazole will increase the stage or result of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.

XCOPRI is often a prescription medicine utilised to deal with partial-onset seizures in Older people eighteen many years of age and more mature.

lasmiditan, diazepam. Possibly improves consequences of another by sedation. Use Warning/Check. Coadministration of lasmiditan and other CNS depressant prescription drugs, including Liquor haven't been evaluated in medical scientific studies. Lasmiditan may possibly result in sedation, and other cognitive and/or neuropsychiatric adverse reactions.

Due to isolated studies of neutropenia and jaundice, periodic blood counts and liver functionality checks are sensible in the course of extensive-time period therapy

stiripentol will decrease the level or outcome of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Check Closely. Think about decreasing the dose of CYP2C19 substrates, if adverse reactions are knowledgeable when administered concomitantly with stiripentol.

Due to the fact diazepam and its metabolites might be present in human breast milk for prolonged periods of time right after acute use, clients need get more info to be encouraged not to breastfeed for an proper stretch of time immediately after obtaining cure